| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2318-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24046
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-204 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-462
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0278
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24046
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6489
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-46 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46 |
| filingDate |
2013-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2021-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-106117364-B |
| titleOfInvention |
Methods of preparing humanized rodents expressing heavy chains comprising VL domains |
| abstract |
The application provides non-human animals, tissues, cells, and genetic material that include modifications of endogenous non-human heavy chain immunoglobulin sequences and include ADAM6 activity that is functional in rodents (eg, mice), wherein the The non-human animal rearranges human immunoglobulin light chain gene segments in the context of a heavy chain constant region and expresses an immunoglobulin-like molecule comprising a human immunoglobulin fused to a heavy chain constant domain A globulin light chain variable domain having homology to a human light chain variable domain fused to a light chain constant domain. |
| priorityDate |
2012-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |