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filingDate 2016-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106117354-B
titleOfInvention A fully human anti-CD47 whole molecule IgG antibody and its application
abstract The present invention discloses a fully human anti-CD47 full-molecule IgG antibody, comprising a light chain variable region and a heavy chain variable region, and the amino acid sequence of the light chain variable region is shown in SEQ ID NO.3, Or a conservative variant obtained by conservative mutation of the sequence through one or more amino acid additions, deletions, substitutions and modifications; and the amino acid sequence of the variable region of the heavy chain is shown in SEQ ID NO.4, Or it is a conservative variant obtained by conservative mutation of the sequence through one or more amino acid additions, deletions, substitutions and modifications. The invention also discloses the DNA molecule, expression vector, host cell and application of the above-mentioned full-molecule IgG antibody.
priorityDate 2016-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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