http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106085936-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-552 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56944 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-315 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-46 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 2016-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106085936-B |
titleOfInvention | A kind of 10 gene-deleted strain of streptococcus suis 2-type and application |
abstract | The invention discloses a kind of 10 gene-deleted strain of streptococcus suis 2-type and application, which is to knock out 10 genes on the basis of streptococcus suis 2-type strong virus force bacterial strain SC to obtain, deposit number are as follows: CCTCC NO:M 2015800.The Strain Virulence is significantly reduced compared with parent strain; it is highly-safe; and immunogenicity is high, the immune attack that can protect immune mouse to resist streptococcus suis 2-type strong virus force bacterial strain of injection, collunarium and oral route illustrates that this vaccine can effectively activate the mucomembranous immune system and systemic immune of host;Meanwhile also there is cross-protection to the streptococcus suis 2-type strong virus force bacterial strain of different ST types.The vaccine preparation mode is simple, is suitble to industrialized production.Simultaneously as the immunogenicity of the mutant strain is similar to wild virulent strain, therefore it can be used as standard items or full bacterium antigen is applied in the development of Quick kit. |
priorityDate | 2016-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.