| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-102
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-765
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4748
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-815 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-84 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-62 |
| filingDate |
2016-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2019-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-106084026-B |
| titleOfInvention |
8 mutant of tumor vascular endothelial cell marker, its fusion protein and application |
| abstract |
The invention discloses a kind of protein mutant of tumor vascular endothelial cell marker 8, the fusion protein and its application in preparation treatment and/or prevention anthrax drug of the protein mutant and human serum albumins.Protein mutant disclosed by the invention significantly improves the affinity with anthrax PA antigen; it is similar to sCMG2 to the inhibitory activity of anthrax toxin; it is 100% to the rat protective rate attacked by anthrax toxin LeTx; after the protein mutant is merged with human serum albumins; nearly 10 times of its prolonged half-life in vivo, the experimental animal attacked by anthrax toxin LeTx can be protected completely in 14 days. |
| priorityDate |
2016-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |