http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106084005-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-08 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K101-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-08 |
| filingDate | 2016-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106084005-B |
| titleOfInvention | Somatostatin receptor-targeted Al18F-NOTA-PEG6-TATE and preparation method and application thereof |
| abstract | The invention discloses Al of a targeted somatostatin receptor 18 F‑NOTA‑PEG 6 -TATE and a preparation method and application thereof. The preparation method of the marker comprises the following steps: the method comprises the steps of connecting a somatostatin derivative TATE with a bifunctional chelating agent NOTA by means of PEG to generate a radioactive labeling precursor, and then carrying out positive electron nuclide by adopting a one-pot method 18 F is marked, namely obtaining 18 F-labelled somatostatin derivatives Al 18 F‑NOTA‑PEG 6 -TATE. The method can be carried out in an acetate buffer solution system or an acetonitrile reaction system, and has the advantages of simple and convenient operation, high labeling rate and high product purity. The positron marker of the targeted somatostatin receptor prepared by the invention can be applied to the preparation of PET/CT molecular probes or tumor treatment drugs, and provides a new idea for the synthesis of clinical PET/CT molecular probes. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102296752-B1 |
| priorityDate | 2016-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.