| abstract |
The invention provides a medical tissue sealing adhesive composition, a medical tissue sealing adhesive and a preparation method and application thereof, wherein the medical tissue sealing adhesive composition comprises the following components: a first component and a second component, wherein the first component comprises: the natural substance containing amino and/or the first modified product modified with sulfydryl on the natural substance containing amino, wherein the natural substance containing amino and the first modified product are respectively and independently provided with more than 10 active groups, and the active groups are amino and sulfydryl; the second component includes: a second modification product in which more than 10 vinyl groups are modified on chitosan and/or polylysine. The medical tissue sealing adhesive has higher rupture strength, lower swelling ratio and good adhesiveness, can quickly close the wound surface of a tissue, effectively plays a role in tissue sealing, prevents tissue fluid, blood or cerebrospinal fluid from leaking, can relieve the pain of a patient, and avoids more dangers. |