http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106075440-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0058 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-223 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 |
| filingDate | 2016-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106075440-B |
| titleOfInvention | A kind of hepatoma-targeting photo-thermal therapy agent and the preparation method and application thereof |
| abstract | The present invention provides a kind of hepatoma-targeting photo-thermal therapy agents and the preparation method and application thereof, belong to biomedical engineering field.Hepatoma-targeting photo-thermal therapy agent of the invention is prepared by the following method to obtain: (1) preparing biotinylation nanometer microvesicle；(2) the biotinylation resisting GPC 3 antibody of Cy7 fluorescent marker is prepared；(3) biotinylation reproducibility graphene oxide (RGO) is prepared；(4) product made from above three step is coupled as biotin-avidin system to obtain hepatoma-targeting photo-thermal therapy agent.Photo-thermal therapy agent of the invention has ultrasound and fluorescence imaging dual function, technology, which is destroyed, by ultrasound targeted microbubble mediates RGO targeting Delivery, monitor photo-thermal therapy process in real time, which can be used for preparing the drug for the treatment of liver cancer, have excellent clinical value. |
| priorityDate | 2015-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.