http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106057394-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01F41-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01F1-344
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01F1-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-531
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01F41-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01F1-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-02
filingDate 2016-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106057394-B
titleOfInvention A kind of preparation method of immune magnetic Nano particulate
abstract The invention belongs to biological technical field, and in particular to a kind of preparation method of immune magnetic Nano particulate.The present invention carries out Surface coating using esters of silicon acis to ferroso-ferric oxide magnetic nanometer particle, reduce its apparent activation energy, so as to greatly improve the stability of magnetic nanometer particle, the concentration cladding thickness of adjustable esters of silicon acis simultaneously, then carboxyl modified is carried out on its surface, whole process reaction condition is gentle, without inert gas environment, without harsh conditions such as HTHPs, without complex appts and large scale equipment, raw material is easy to get, without a large amount of organic solvents, simultaneously synthesizing magnetic particle particle diameter is controllable, free amine group after the magnetic particle of carboxyl modified is activated by activator with bioactive molecule passes through amido link covalent bond, it is more firm compared to the imine structure of aldimine condensation reaction and the Non-covalent binding of collaurum.
priorityDate 2016-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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