http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106053665-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
filingDate | 2016-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106053665-B |
titleOfInvention | A method of with the related substance of HPLC separation determination ipragliflozin proline bulk pharmaceutical chemicals |
abstract | The present invention relates to a kind of with method of the HPLC separation determination ipragliflozin proline bulk pharmaceutical chemicals in relation to substance, includes the following steps:It is that Mobile phase B carries out gradient elution using water as mobile phase A, acetonitrile, flow velocity is 0.8~1.2mL/min, and column temperature is 28~32 DEG C, is detected to ipragliflozin using UV detector using octadecylsilane chemically bonded silica as filler;Using octadecylsilane chemically bonded silica as filler, using the mixed liquor of first alcohol and water as mobile phase, proline is detected using UV detector.The method of the present invention is by considering analytical column, mobile phase, gradient elution program and flow velocity, column temperature to the combined influence of separation detection, so that testing result has reached optimization, have the advantages that fast and convenient, high sensitivity, accurate and reliable, the related substance suitable for separation determination ipragliflozin proline bulk pharmaceutical chemicals. |
priorityDate | 2016-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 104.