abstract |
A dry powder inhaler and system for drug delivery are provided. Dry powder inhalers can be provided with or without a unit metering cartridge for the inhaler. The inhaler and/or cartridge may be provided with a drug delivery formulation including, for example, diketopiperazine and including peptides and proteins such as insulin and glucagon-like peptide 1 for the treatment of diabetes and/or obesity. Dry powder inhalers are compact; available in a variety of shapes and sizes, colors, and include a housing, a spout, a cartridge placement area, and a mechanism for opening and closing the drug cartridge. The device is easy to manufacture and provides a pre-metered single metering cartridge that is relatively easy to use and can be reused or disposed of at will. |