http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106008621-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-00 |
| filingDate | 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106008621-B |
| titleOfInvention | A kind of synthetic method and its midbody compound of morphine -6- β-D-Glucose aldehydic acid glycosides |
| abstract | The invention discloses a kind of morphine -6- β-D-Glucose aldehydic acid glycosides synthetic methods and its midbody compound.This method comprises the following steps: (1) 3- acetylmorphine is reacted in organic solvent 1 under Louis acid catalysis with the glucuronate that acyl group is protected, and obtains intermediate shown in formula (IV)；(2) intermediate shown in formula (IV) is hydrolyzed in the admixture solvent of C1-C4 alkane alcohol and water using lithium hydroxide, hydrobromic acid is neutralized, and is washed with C1-C4 alkanol, it is dry to get；The definition of substituent group is detailed in specification in formula (III) and (IV).Synthetic method of the invention has the advantages that easy to operate, mild condition, high income and is easy to industrialized. |
| priorityDate | 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.