http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106008391-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D275-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-06 |
| filingDate | 2016-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106008391-B |
| titleOfInvention | A kind of preparation method of -3 (2H) -one of 2- phenyl -1,1- dioxy -1,2- benzisothiazoles |
| abstract | The present invention relates to a kind of preparation method of 2 phenyl, 1,1 dioxy, 1,2 benzisothiazole 3 (2H) ketone, including：(1) aniline, water and fluoborate aqueous solution are mixed, sodium nitrite in aqueous solution then is added dropwise under 0~5 DEG C of stirring, is added dropwise and is warmed to room temperature, continue to be stirred to react 1~2h, filtered, obtain phenyldiazonium tetrafluoroborate；(2) at 5 DEG C~5 DEG C by 1,1 dioxy 1,2 benzisothiazole 3 (2H) ketone, alkali, copper salt catalyst and stirring solvent mixing, then phenyldiazonium tetrafluoroborate is added portionwise, 5 DEG C~be stirred at room temperature 6~8h of lower reaction, extraction after the completion of reaction, it is dry, boil off solvent, recrystallization to get.The present invention shortens the reaction time, while improve yield using mantoquita as catalyst；Preparation method starting material is easy to get, at low cost, and operation is simple, and reaction route is short, is easy to industrialized production, has a good application prospect. |
| priorityDate | 2016-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.