http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106008249-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-04 |
| filingDate | 2016-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106008249-B |
| titleOfInvention | A kind of synthetic method of the aminosalicylic acid of mesalazine pharmaceutical intermediate 5 |
| abstract | The invention discloses a kind of synthetic method of the aminosalicylic acid of mesalazine pharmaceutical intermediate 5, this method passes through in sodium sulfite and the nitropyridine mixed solution of 2 hydroxyl, 5 methyl 3, azobenzene salicylic acid and molybdenum chloride are subjected to temperature rising reflux reaction, then xylene solution is added, cooling, solid, recrystallization are separated out, after being dissolved with oxalic acid solution, molecular sieve decolourizes, filtered, cooling filtering, dehydration, obtains 5 aminosalicylic acids.This method compares the synthetic method in background technology, and the reaction time substantially shortens, and reaction yield greatly improves, while the invention provides a kind of new synthetic route, is laid a good foundation for further lifting reaction yield. |
| priorityDate | 2016-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.