| abstract |
The invention discloses a preparation method of chlorogenic acid and similar compounds thereof, comprising the following steps: S1: reflux extraction with an extractant; S2: concentrating the extract into an extract; S3: dissolving the extract and using acetic acid Ethyl ester extraction; S4: adjust the pH value of the concentrated solution after extraction to be neutral, and filter through a macroporous resin column; S5: use a thin layer to prepare a plate, use a developing agent to develop, scrape, grind, pack, wash, Concentrate and dry to obtain high-purity chlorogenic acid and its similar compounds. The method described in the present invention has clear flow, simple method and low cost, and the product obtained by purification has good color, high yield and purity, and can obtain multiple chlorogenic acid-like compounds at the same time, which can be obtained for chlorogenic acid and its similar compounds It provides a basis for more extensive and effective application. |