http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105999308-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-108 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 |
| filingDate | 2016-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105999308-B |
| titleOfInvention | Tumor targeting MRI contrast agent and preparation method thereof |
| abstract | The invention provides a tumor targeting MRI contrast agent and a preparation method thereof, which is characterized in that: the contrast agent comprises a small molecular gadolinium chelate part and a targeting carrier part, wherein the small molecular gadolinium chelate part and the targeting carrier part are coupled through a covalent bond; wherein the small molecular gadolinium chelate part is Gd-DO 3A; the targeting vector moiety comprises an EBP molecule. The contrast agent has good relaxation enhancing capability, can be combined with EGFR of tumor cells in a targeted manner, has strong targeted contrast effect, and prolongs the imaging time of the contrast agent in vivo, thereby reducing the additive amount of the contrast agent and having strong practicability. |
| priorityDate | 2016-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.