http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105997936-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5161 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5192 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 |
filingDate | 2016-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105997936-B |
titleOfInvention | A kind of preparation method of carboxymethyl chitosan nano particle immobilization porous multilayer sodium alginate glueballs |
abstract | The invention discloses a kind of technologies of preparing of nanoparticle immobilization glueballs for drug oral delivering, carboxymethyl chitosan nano particle evenly dispersed in aqueous solution, is fixed in multi-layer porous sodium alginate glueballs by i.e. a kind of preparation method of carboxymethyl chitosan nano particle immobilization porous multilayer sodium alginate glueballs by inner ion cross-linking method.The characteristic that there is the polytrope stomach juice-resistant and enteron aisle to be disintegrated discharges rapidly out carboxymethyl chitosan nano particle in enteron aisle neutrality and weakly alkaline environment.The defect that can not only effectively overcome carboxymethyl chitosan nano particle unstable under the conditions of gastric acid is more able to extend release time of the carrying medicament in enteron aisle, improves the oral delivery efficiency of drug.It can be used for biomaterial for medical purpose and pharmaceutical carrier, there are good research and development Utilization prospects. |
priorityDate | 2016-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.