http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105985371-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 |
| filingDate | 2015-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105985371-B |
| titleOfInvention | Prepare key intermediate and its application of limaprost |
| abstract | The present invention provides compounds shown in the key intermediate formula B of synthesis limaprost, in formula, R 1 Selected from t-Butyldimethylsilyl, tert-butyl diphenyl silicon substrate, triethyl group silicon substrate, trimethyl silicon substrate or THP trtrahydropyranyl；R 2 Selected from t-Butyldimethylsilyl, tert-butyl diphenyl silicon substrate, triethyl group silicon substrate, trimethyl silicon substrate or THP trtrahydropyranyl；R 4 Selected from acetyl group, chloracetyl, Methoxyacetyl, benzoyl or substituted benzoyl；And R 6 Selected from-CH 2 OH or-CHO.The present invention also provides the routes using the compound synthesis limaprost.The advantages such as the route has the control of preparation process chirality preferably, is reacted by multiple Wittig and constructs double bond structure, processing efficient, and production cost is low. |
| priorityDate | 2015-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.