| abstract |
For the novel composition from sample removal impurity (such as protein masses) containing interested albumen (for example, antibody).This composition can be used before the virus filtration step in protein purification procedures, to remove aggregation and protection virus filter from silting up, therefore improve virus filter capacity.Porosu solid support including the copolymer at least two monomers, wherein at least one of described monomer includes acrylamide and at least second comonomer includes hydrophobicity conjugated group, thus the wherein solid support selective binding protein aggregation separates interested monomeric protein with protein masses.The method can be carried out under the conditions of neutral supreme pH and high conductivity. |