http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105968081-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-96 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 2016-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105968081-B |
titleOfInvention | A series of spirolactone-type Ent-kaurane diterpenoid derivatives with antibacterial activity |
abstract | The present invention relates to natural drug and field of medicinal chemistry, and in particular to a series of spirolactone-type Ent-kaurane diterpenoid derivatives and its preparation method and application with antibacterial activity, the spirolactone-type Ent-kaurane diterpenoid derivative have the following structure:Wherein, R 1 Replace the fatty acyl group containing 1-8 carbon atom, aromaticacyl radical or halogen substituted aroma acyl group containing 1-12 carbon atom for oxo, the fatty acyl group containing 1-8 carbon atom, halogen;R 2 For the alkyl containing 1-8 carbon atom, the naphthenic base of 3-8 carbon atom, aromatic rings or halogenated aromatic ring, 5-12 carbon atom aryl heterocycle or halogenated heteroaromatic containing 5-12 carbon atom include the hetero atom of 1-3 N, O or S in the heteroaromatic. |
priorityDate | 2016-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.