http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105963050-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-022 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-02 |
filingDate | 2016-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105963050-B |
titleOfInvention | The manufacture method of engineering blood vessel lobuli hepatis |
abstract | A kind of manufacture method of engineering blood vessel lobuli hepatis, comprises the following steps:The supportive frame of compatibility of lobuli hepatis is printed with 3D printer, the mould that seven glass capillaries constitute lobuli hepatis is inserted in the frame;HepG2 cells and temperature-sensitive hydrogel solution are mixed by cell concentration 10^6cells/mL, dosed in the mould, with ultraviolet light 30s 200s, solidifies and extracts glass capillary after crosslinked with collagen out, form capillary channel;Configuration concentration is 1*10^7cells/mL Human umbilical vein endothelial cells, is injected into the capillary channel and cultivates, it is covered with capillary channel inwall, so that the lobuli hepatis of vascularization is made.Lobuli hepatis good biocompatibility made from this method, drug screening, pathogenic mechanism research and the research of medicine metabolic process in liver available for liver class medicine. |
priorityDate | 2016-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.