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filingDate 2016-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105954277-B
titleOfInvention A kind of method, apparatus for evaluating skin irritation and its application
abstract External medicine preparation and cosmetics are both needed to carry out skin irritation inspection, conventional method judges the degree of skin irritation using the dermoreaction after living animal smearing tested products, cost be present compared with place of the deficiencies of high, the test period is long, individual difference is big, animal ethics.In consideration of it, the present invention provides a kind of device for evaluating skin irritation:Indicator is encapsulated in liposome to prepare liposome artificial skin membrane and be attached in film nested arrangement.In use, liposome artificial skin membrane surface smear judges skin irritation power after by test product, by indicator color in the acceptable solution of receiving chamber.The method cost is low, efficiency high, controllability and reappearance are high, and experiment confirms that its test result and animal test results are basically identical, so as to substitute zoopery, economy and time cost are saved, strong technical guarantee is provided for the safety evaluatio of external medicine preparation and cosmetics.
priorityDate 2016-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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