http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105939601-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-0226 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K15-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N1-02 |
| filingDate | 2015-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105939601-B |
| titleOfInvention | Stabilization of whole blood at room temperature |
| abstract | The present disclosure relates to stabilizing nucleated cells in a whole blood sample ex vivo by being an additive to a liquid composition for stabilizing an analyte in intact nucleated cells of a whole blood sample ex vivo, the composition being an aqueous solution comprising an anticoagulant, a phosphate salt, a cell metabolizable sugar, adenine and an antioxidant, wherein the antioxidant comprises a mitochondrially targeted antioxidant, preferably a mitochondrially targeted antioxidant selected from the group consisting of SkQ1, MitoQ, SS-31, and mixtures thereof. In a specific embodiment, the liquid composition further comprises a protease inhibitor. Further provided are advantageous uses of the composition for stabilizing an analyte selected from the group consisting of DNA, RNA and protein in intact nucleated cells of a whole blood sample ex vivo and kits comprising the composition for performing the uses. In addition, specific methods for stabilizing intact nucleated cells of a whole blood sample ex vivo are provided. |
| priorityDate | 2014-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 553.