http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105924403-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 |
| filingDate | 2016-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105924403-B |
| titleOfInvention | A kind of ring propane diamide compound with anti-tumor activity and its preparation method and application |
| abstract | The present invention provides a kind of ring propane diamide compounds with anti-tumor activity and its preparation method and application, and the structural formula of the compound is Wherein R 1 For halogen group, R 2 For halogen group or Or R 1 、R 2 It is collectively formed The compound has good inhibitory activity to 2 kinases of VEGFR, can be by the activity of inhibition 2 kinases of VEGFR, and the signal path for blocking it to induce inhibits hyperplasia and the migration of tumour cell, so as to the preparation applied to antitumor drug.And the preparation method of the compound is easy to get with raw material, reaction condition is mild, and reaction process is easy to operate, the cheap advantage of agents useful for same. |
| priorityDate | 2016-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.