http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105924342-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-782 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23B7-154 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-74 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23B7-154 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-02 |
| filingDate | 2016-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105924342-B |
| titleOfInvention | 1,5- bis--(2,4- dihydroxy-phenyl) -3-(3,4- dihydroxy-phenyl)-pentane -1,5- diketone synthetic method and its application |
| abstract | The invention discloses the synthetic methods and its application of 1,5- bis--(2,4- dihydroxy-phenyl) -3- (3,4- dihydroxy-phenyl)-pentane -1,5- diketone, belong to food, cosmetics and field of medicaments.The present invention passes through 3,4- 4-dihydroxy benzaldehyde and 2,4- resacetophenone under boric acid and ascorbic catalysis in PEG400 be solvent reaction 6 hours, a kind of efficient tyrosinase inhibitor of green syt, it is separated using silica gel column chromatography and gel filtration chromatography, obtains the sterling of the potent tyrosine enzyme inhibitor.It is parsed through mass spectrum and nuclear-magnetism, determine that the substance is 1,5- bis--(2,4- dihydroxy-phenyl) -3- (3,4- dihydroxy-phenyl)-pentane -1,5- diketone [1,5-bis- (2,4-dihydroxy-phenyl) -3- (3,4-dihydroxy-phenyl)-pentane-1,5-dione].Compound provided by the invention can be effective for the inhibition of the enzymatic browning of fruits and vegetables, skin-lightening cosmetic and preparation for preventing and treating human pigmentation's property disease caused by melanism, melanoma and other pharmaceutical preparations for needing to inhibit tyrosinase activity. |
| priorityDate | 2016-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.