| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef984517ad4fa88458ab2a9b88ab9961 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4893
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-33 |
| filingDate |
2014-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a1bb50913d911850565cd54d24ebfb8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6055ae273acc4d675362561ca05413ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5613b8e7925d9a1efdab49559e7b3faa |
| publicationDate |
2016-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-105916875-A |
| titleOfInvention |
Polyprotease Therapeutics for Chronic Pain |
| abstract |
The present invention includes Clostridium neurotoxin derivatives comprising at least two light chain endopeptidase domains, and nucleic acids encoding said Clostridium neurotoxin derivatives. In preferred embodiments, the present invention includes methods and compositions for the treatment of inflammatory conditions such as arthritis; chronic pain such as neuropathic pain and inflammatory pain by using said Clostridium neurotoxin derivatives, said Clostridium neurotoxin derivatives include those derived from intact BoNT/A with an LC/E-derived endopeptidase linked to an LC/A endopeptidase. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109790204-A |
| priorityDate |
2013-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |