http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105911096-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ce97695dd3c231c29cec9edbeae45ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5d1d6d8a0df0589b1282729c0ad453ce |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-00 |
| filingDate | 2016-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b16a722813eb55e6ec4b1e38f8cad03b |
| publicationDate | 2016-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105911096-A |
| titleOfInvention | Artificial heart system for in-vitro drug pharmacology and toxicology screening |
| abstract | The invention discloses an artificial heart system for in-vitro drug pharmacology and toxicology screening. The artificial heart system comprises regenerated myocardial tissue, a myocardial tissue support structure, a myocardial nutrient solution and a vessel. The regenerated myocardial tissue comprises myocardial cells and collagen. The collagen is used for forming a skeleton structure between myocardial cells so that myocardial cells are fixed in the skeleton structure and the artificial heart tissue can form a three-dimensional structure with a fixed form. The regenerated myocardial tissue is fixed to the myocardial tissue support structure and is immersed in the myocardial nutrient solution in the vessel. The in-vitro human myocardial cell tissue produced through human pluripotent stem cell (hPSC) induction provides a human heart platform for drug development, can test drug pharmacology and toxicology effects and reduces a test patient risk and a drug development cost. The artificial heart system is used for clinical scientific research such as individual patient treatment or patient specific disease model building and satisfies individual medical requirements. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110231468-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108467835-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108467835-A |
| priorityDate | 2016-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.