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filingDate 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105907632-B
titleOfInvention genetically engineered biological indicator
abstract The invention discloses a kind of genetically engineered biological indicator, biological monitoring for one or more sterilities, it is imported foreign gene in indicator microoraganism by technique for gene engineering means, and foreign gene includes promoter, reporter gene and selected marker.Wherein selected marker is located at inducible promoter upstream, and reporter gene is located at inducible promoter downstream.In the presence of without inducer, selected marker's expression, reporter gene transfects successful bacterial strain without expression for screening.After sterilizing factor exposure, indicator microoraganism isogeneous induction thing is in contact, reporter gene expression.The present invention without enzyme-specific substrate, can autofluorescence, while also there is higher to-noise ratio, fluorescence signal is strong, easily detects, a variety of advantages such as sensitivity height.
priorityDate 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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