http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105906714-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-101 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2469-20 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56911 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-23 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
filingDate | 2016-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105906714-B |
titleOfInvention | A kind of preparation and application of brucellosis specific fusion protein antigen |
abstract | The invention discloses a kind of brucellosis specific fusion protein antigens, it is that the amino acid sequence of brucella outer membrane protein BP26, OMP31, OMP16, OMP2b dominant antigen epitope is connected, construct antigen-4 fusion protein gene, it is inserted into pET-28b, in the fusion protein of e. coli bl21 (DE3) expression, close to native protein in conformation, and the antigenicity and solubility of native protein are maintained, and be prepared for people's brucellosis antibody ELISA kit using it as diagnostic antigen.The kit, which overcomes traditional etiological diagnosis and is separately cultured, to be increased bacterium time length, is easy to pollute the environment and infect the deficiency of people, while can improve the serious disadvantage of traditional immunization method cross reaction.The detection method has the advantages that high specificity, reproducible, high sensitivity, provides means for the quick, accurate of brucellosis, specific diagnostic, also provides foundation for the morning diagnosis of Brucellosis Patients, early treatment. |
priorityDate | 2016-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 476.