http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105906656-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-73 |
| filingDate | 2016-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105906656-B |
| titleOfInvention | A kind of gram of azoles replaces the synthetic method of Buddhist nun's intermediate |
| abstract | The present invention relates to small-molecule chemical field of medicine preparing technology, and in particular to a kind of gram of azoles replaces the preparation method of Buddhist nun's intermediate, and described preparation method includes：(1) compound 1 and compound 2 are through flowing chemical synthesis compound 3；(2) compound 3 that step (1) obtains replaces Buddhist nun's intermediate I with boric acid ester compound 4 through flowing chemical synthesis gram azoles.Provided by the invention gram of azoles replaces the preparation method of Buddhist nun's intermediate, and yield is higher, gram azoles can be greatly reduced for energy consumption and cost in Buddhist nun's preparation process, environmentally friendly, security is good, and automaticity is high, suitable for industrial amplification production.Reaction scheme is as follows： Wherein, Y is leaving group, and Z is amido protecting group, and X is selected from：F、Cl、Br、I. |
| priorityDate | 2016-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 134.