http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105902546-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 |
| filingDate | 2014-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105902546-B |
| titleOfInvention | Application of the substituted piperazine -1,4- diamide compound in the medicine of preparation treatment and/or prevention of inflammation reaction |
| abstract | The present invention relates to application of the substituted piperazine -1,4- diamide compound in pharmacy.Substituted piperazine -1,4- diamide compound can be used as the activator of SIRT1, exciting nuclear receptor LXR α and LXR β, adjust the expression of target protein ABCA1/G1, promote lipid and cholesterol efflux, adjust the expression of expression, adjusting aging related genes p66shc of inflammation key protein p65 etc., the adjustment effect to cholesterol metabolic, inflammation correlation and aging gene or albumen is played, for treating cardiovascular and cerebrovascular disease, adjusting blood lipid, antiatherosclerosis illness, anti-inflammatory response and anti-aging disease. |
| priorityDate | 2014-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 245.