http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105902500-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-606 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 |
filingDate | 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105902500-B |
titleOfInvention | A kind of mesalazine enteric positioning controlled-release preparation and preparation method thereof |
abstract | The invention discloses a kind of mesalazine enteric positioning controlled-release preparations, it is successively made of from inside to outside inner core, controlled release coating layer, adherency coatings, enteric coat layer, the inner core includes mesalazine, hydroxypropyl cellulose and talcum powder, the controlled release coating layer is made of ethyl cellulose, triethyl citrate, the adherency coatings use sodium alginate, and the enteric coat layer is made of methacrylic acid and methylmethacrylate copolymer, triethyl citrate and talcum powder.The present invention also provides the preparation method of above-mentioned enteric positioning controlled-release preparation, preparation method of the invention is easy, parameter is controllable, and the pellet being prepared does not release the drug under the conditions of gastric acid, can slowly release the drug 24 hours under the conditions of pH7.5 dissolution medium.Preparation adheres to no irritation to gastrointestinal tract, can be used for treating the acute stages treated of ulcerative colitis (inflammation is with ulcer) and the maintenance therapy of prevention recurrence. |
priorityDate | 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.