http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105899681-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2537-143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6851 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 |
filingDate | 2014-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105899681-B |
titleOfInvention | Method for multiplex detection of alleles associated with ophthalmic conditions |
abstract | Systems and methods are disclosed for detecting at least two genomic alleles associated with corneal dystrophy in a sample from a human subject, wherein the subject's cells (eg, epithelium) are attached to the tip of a substrate. The tip of the substrate is agitated in a lysis solution that lyses cells attached to the substrate. The substrate is removed from the lysis solution when this agitation is complete. The resulting lysis solution is incubated, and then genomic DNA is isolated from the lysis solution to form a gDNA solution. From this, the identity of at least two nucleotides present in the human TGFpI gene was identified using at least two oligonucleotide primer pairs and gDNA solution. The at least two nucleotides are located at separate independent positions in the TGFpI gene, which correspond to separate independent single nucleotide polymorphisms (SNPs) associated with corneal dystrophy. |
priorityDate | 2013-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 153.