http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105891314-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2570-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
filingDate | 2016-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105891314-B |
titleOfInvention | A kind of method of iTRAQ technology screening myocardial infarction disease expression albumen |
abstract | The invention discloses a kind of methods of iTRAQ technology screening myocardial infarction disease expression albumen, by isotope labelling is opposite and absolute quantitation proteomic techniques screening early myocardial infarction disease patient groups' serum in differential expression protein, single sample T check analysis is carried out by the mass spectral results to the blood serum sample after two group echos, find 6 highly expressed albumen, 1 is high expression in normal group, and 5 are expressed to be high in early myocardial infarction disease group.Wherein, Leucine-rich alpha-2-glycoprotein albumen coverage and unique peptide number of segment highest in disease group, its peptide fragment is confirmed there is also significant difference by the analysis of peptide segment data, finds that this albumen may be related to the processes such as thrombosis by gene ontology functional annotation analysis.The advantages such as the method for the present invention has high resolution, flux is big, speed is fast, open up a new way for the screening of such disease protein marker. |
priorityDate | 2016-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.