http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105884917-B

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B33-00
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-16
filingDate 2016-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105884917-B
titleOfInvention A kind of linear dextrin base liposome and preparation method thereof
abstract A kind of linear dextrin base liposome and preparation method thereof, belongs to starch extract field of deep.The present invention is based on linear dextrins to have this characteristic of reducing end, using the degree of polymerization(DP)30 35, the linear dextrin of dispersiveness 1.12 1.25 is raw material, amino is introduced into the reducing end of linear dextrin molecule by reduction amination, using the linear dextrin of the end group amination γ benzyl L glutamic acid N CA ring-opening polymerisations is triggered to form amphiphilic linear dextrin, and the linear dextrin base liposome that grain size is 100 250 nm is prepared by nanoprecipitation method.The preparation process of the present invention is simple to operation, low raw-material cost be easy to get to, and prepared linear dextrin base liposome structure stability is good, it is not susceptible to fusion rupture, and there is good biocompatibility, nontoxicity and biodegradable, it has broad application prospects in fields such as drug delivery, gene therapy, bio-imaging, enzyme reactors.
priorityDate 2016-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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