abstract |
The invention relates to a tanshinone I derivative, a preparation method and application thereof. The compound is a furan ring 2-substituted amide methylene modifier in the structural formula of tanshinone I, tanshinone I serves as the raw material, and the novel tanshinone derivative is prepared through a chemical synthesis method and can be used for treating cancers, serving as a tumor multi-drug resistance reversing agent, assistant medicine and a CYP1 family specific inhibitor, treating cardiovascular and cerebrovascular diseases, serving as a carboxylesterase inhibitor, treating androgen related diseases and serving as antibacterial. |