abstract |
The invention discloses a kind of polycyclic compound, preparation method, pharmaceutical composition and applications.Polycyclic compound (I), its isomers, prodrug, stable isotope derivatives or pharmaceutically acceptable salt of the invention has the following structure.Polycyclic compound of the invention has good IDO and/or TDO inhibiting effect, can effectively treat, alleviates and/or prevent various related diseases, such as tumour, communicable disease and immunological diseases due to caused by immunosupress relevant to IDO and/or TDO etc.. |