http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105884698-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-74
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-61
filingDate 2016-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105884698-B
titleOfInvention A kind of synthetic method of diphenyl substituted quinazoline compounds
abstract The present invention relates to a kind of synthetic methods of quinazoline compound shown in lower formula (III), the method includes in a solvent, in the presence of catalyst, containing n-donor ligand, acid accelerator and alkali, lower formula (I) compound reacts with lower formula (II) compound, it is post-treated after reaction, to obtain the formula (III) compound Wherein, R 1 、R 2 It is each independently selected from H, C 1 ‑C 6 Alkyl or C 1 ‑C 6 Alkoxy.The method by the comprehensive selection of novel suitable substrates, catalyst, containing n-donor ligand, acid accelerator and alkali and solvent etc. with cooperate with, to expand the range of substrate, and quinazoline compound can be obtained with good yield, to have a good application prospect in organic chemical synthesis field and researching value, completely new method is provided for the synthesis of such compound.
priorityDate 2016-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 55.