http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105884698-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-74 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-61 |
filingDate | 2016-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105884698-B |
titleOfInvention | A kind of synthetic method of diphenyl substituted quinazoline compounds |
abstract | The present invention relates to a kind of synthetic methods of quinazoline compound shown in lower formula (III), the method includes in a solvent, in the presence of catalyst, containing n-donor ligand, acid accelerator and alkali, lower formula (I) compound reacts with lower formula (II) compound, it is post-treated after reaction, to obtain the formula (III) compound Wherein, R 1 、R 2 It is each independently selected from H, C 1 ‑C 6 Alkyl or C 1 ‑C 6 Alkoxy.The method by the comprehensive selection of novel suitable substrates, catalyst, containing n-donor ligand, acid accelerator and alkali and solvent etc. with cooperate with, to expand the range of substrate, and quinazoline compound can be obtained with good yield, to have a good application prospect in organic chemical synthesis field and researching value, completely new method is provided for the synthesis of such compound. |
priorityDate | 2016-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.