http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105879123-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18 |
filingDate | 2016-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105879123-B |
titleOfInvention | PLGA fiber-microspheres are double to carry medicine compound rest and preparation method thereof |
abstract | The invention discloses double load medicine compound rests of a kind of PLGA fiber-microspheres and preparation method thereof, for solving the existing technical problem for preparing the double method complexity for carrying medicine compound rests of PLGA fiber-microspheres.Technical solution is to prepare the electrostatic spinning liquid containing statins using PLGA fibers and statins, then use PLGA fibers with bioactie agent in mass ratio for 20~600000:1 prepares uniform EFI solution, finally by the electrostatic spinning liquid of preparation and EFI solution while electrospinning and EFI, the timbering material of collection is placed in vacuum drying chamber dry 24~48h, obtains the PLGA fiber-microsphere compound support frame materials of statins and the double loads of bioactie agent.Due to the method using lotion EFI, water-in-oil emulsion is formed, avoids drug from being in direct contact with organic solvent and causes to inactivate, method is simple.Simultaneously because surfactant and emulsifier, biological safety higher is not used in preparation process. |
priorityDate | 2016-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.