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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_20690a5e51f5f3def8f2a44a12ebec56
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-00
filingDate 2014-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb4ccfa8411f1113681c945191ea4fbe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51e87f961e47c9b285383ee11430547f
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publicationDate 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105878270-A
titleOfInvention Application of deuterium-depleted water as tumor multidrug-resistance reversal agent
abstract The invention belongs to the field of medicine, and relates to an application of deuterium-depleted water (DDW) in reversing tumor multidrug resistance and an application as an antineoplastic drug sensitizer. The deuterium-depleted water, which has an effect of reversing the multidrug resistance of tumor cells as a natural product, can be used as a tumor multidrug-resistance reversal agent; and meanwhile, the deuterium-depleted water, which has an effect of enhancing the sensitivity of tumor multidrug-resistance cells to an antineoplastic drug, can be used as the antineoplastic drug sensitizer. The deuterium-depleted water provided by the invention, as ab adjuvant therapy agent for tumor therapy, can be independently used or used in a mode of combining with one or more antineoplastic drugs selectively. The invention also relates to independent use of the deuterium-depleted water or the combined use of the deuterium-depleted water with one or more antineoplastic drugs in daily tumor therapy, wherein the deuterium content in the deuterium-depleted water is 0.01-100ppm.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108969475-A
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priorityDate 2014-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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