http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105878245-B
Outgoing Links
Predicate | Object |
---|---|
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4704 |
filingDate | 2015-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105878245-B |
titleOfInvention | A kind of preparation method of Rebamipide water slurry |
abstract | The present invention discloses a kind of preparation method of Rebamipide water slurry, comprises the following steps:(1), all auxiliary materials are dissolved in water for injection, obtain the auxiliary material aqueous solution;(2), Rebamipide is added in the auxiliary material aqueous solution obtained by step (1), is crushed and is disperseed, obtains Rebamipide water slurry just liquid;(3), by the Rebamipide water slurry obtained by step (2), just liquid carries out high-pressure homogeneous again, finally obtains the water slurry containing Rebamipide;(4), the Rebamipide water slurry obtained by step (3) is sterilized, then it is aseptic subpackaged in for the container of Clinical practice.Compared with prior art, the preparation method of Rebamipide water slurry of the invention, obtained Rebamipide water slurry, 1 μm of Rebamipide average grain diameter <, change of size is little after high-temperature sterilization, and the long-term particle diameter that stores will not increase. |
priorityDate | 2015-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.