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filingDate 2015-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105861535-B
titleOfInvention The biological preparation method of typhoid fever glycoprotein and its application
abstract The invention discloses a kind of biological preparation method of typhoid fever glycoprotein and its applications.The present invention discloses a kind of preparation method of the albumen of bacterial polysaccharides modification, including co-expressing the substrate protein of Neisseria meningitidis O- oligosaccharide transferring enzyme PglL in the bacterium of O- antigen ligase gene defect with Neisseria meningitidis O- oligosaccharide transferring enzyme PglL, the albumen of bacterial polysaccharides modification is obtained.The present invention improves the production efficiency of vaccine, reduces cost, be with a wide range of applications, can be used for preventing disease caused by typhoid fever pathogen in the homogeneity for improving vaccine.
priorityDate 2015-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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