http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105861339-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-6427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-04016 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-64 |
| filingDate | 2016-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105861339-B |
| titleOfInvention | Recombination Mortierella alpina, its construction method and the application of one plant of overexpression GTP cyclohydrolase gene |
| abstract | The present invention relates to recombination Mortierella alpina, its construction method and applications that one plant is overexpressed GTP cyclohydrolase gene.The present invention constructs the overexpression engineered strain of GTPCH1 gene in tetrahydrobiopterin route of synthesis, to explore BH 4 Effect during Mortierella alpina lipid synthesis.The present invention constructs the recombinant bacterial strain of one plant of overexpression GTPCH1 gene using Agrobacterium-Mediated Transformation.The relative expression levels of GTPCH1 gene improve 2 times or so in recombinant bacterial strain, and total lipid content improves about 37% than wild type M Mortierella, while the relative amount of NADPH improves 2 times or so.This shows that GTPCH1 plays a significant role during lipid synthesis, it is likely to the important regulating and controlling factor of NADPH needed for lipid synthesis.The invention is deeply to parse Mortierella alpina lipid synthesis mechanism, and the cell factory for making production functional lipids provides theoretical foundation. |
| priorityDate | 2016-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 674.