| abstract |
The present invention belongs to the field of bio-medicine materials, and in particular relates to a PVP modified magnetic-fluorescent core-shell La1-xSrxMnO3 / ZnO nanocomposite particle and preparation method thereof. La1-xSrxMnO3 is used as a core, and ZnO is used as a shell; the shell surface is modified by a surfactant PVP; x satisfies the relation of: 0.1<=x<=0.8; the core diameter is 20-80 nm; and the shell thickness is 5-10nm. A preparation method is as below: under the effect of the surfactant PVP, a two-step continuous reaction is conducted to prepare the La1-xSrxMnO3 / ZnO nanocomposite particle. The nanocomposite particle prepared by the invention has excellent biocompatibility, chemical stability, magnetic properties, optical absorption performance and fluorescent activity, and has wide range of application in magnetic hyperthermia, drug delivery and release, biosensors and immunodiagnosis. |