http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105859774-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5022 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-50 |
| filingDate | 2016-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105859774-B |
| titleOfInvention | A kind of preparation method of phosphine benzene-like compounds |
| abstract | The present invention relates to a kind of preparation method of phosphine benzene-like compounds, bromine benzene-like compounds and reactive magnesium first is made into RMgBr, then be catalyzed bromine benzene-like compounds RMgBr with tetrakis triphenylphosphine palladium and reacted with phosphine chlorine compound.Specific method is, under inert gas shielding, bromine benzene-like compounds and magnesium chips and organic solvent is made into RMgBr, flowed back 2 10 hours；Tetrakis triphenylphosphine palladium is added at room temperature, is stirred 10 minutes to 3 hours, and phosphine chlorine compound, back flow reaction 1 10 hours is added dropwise in room temperature；Saturation strong acid weak base saline solution is added dropwise into reaction solution under ice-water bath, liquid separation, organic phase precipitation, adds alcoholic solvent to crystallize, is filtrated to get phosphine benzene-like compounds.The preparation method of the present invention, which not only greatly improved, prepares yield, and post-processes simply, eliminates the process washed repeatedly with ammoniacal liquor, simplifies preparation technology, is advantageous to large-scale industrial production. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3766891-A4 |
| priorityDate | 2016-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.