http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105859616-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_215fd62f148bc5aab2bfc8e46ecd6126 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-22 |
| filingDate | 2016-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fda2b30d7a84e3385ca367e79c9dfd2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_353dbf19b4c02346f78de870c515f9f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7ae1c11d92758953fcbadafe256c2cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29cd07a7c0bda410d4893aca2a47ffac |
| publicationDate | 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105859616-A |
| titleOfInvention | A kind of preparation method of multi-substituted isoquinoline derivatives |
| abstract | The invention discloses a method for preparing multi-substituted isoquinoline derivatives. The method belongs to the technical field of organic synthesis. The method comprises: adding isothiocyanate and diaryl hypervalent iodide into a reactor, Under catalysis, heat in a solvent, cool to room temperature after the reaction is complete, extract the system with ethyl acetate, then concentrate the filtrate with a rotary evaporator to obtain a crude product, and finally separate the product by column chromatography. The synthesis method has simple operation, easy preparation of raw materials, simultaneous introduction of multiple substituents, easy purification and separation of products, high yield, and is suitable for synthesizing multi-substituted isoquinoline derivatives. Its reaction equation is as follows: |
| priorityDate | 2016-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.