| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94001306c54a145505ed0a920d915745 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F2438-03 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F293-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F293-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0041
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F293-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-711 |
| filingDate |
2016-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90920a347ad0e1c96ee66c605db6e1b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81e7509baf108c4e4da3174345a399e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c94b426e91deb9ae227d49e939b183e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19579ca2756f48d4e2734d376b615255
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcb226af19312d5fcb0b1576213e43fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5f70c940dca6e0d4396422518cd92c9 |
| publicationDate |
2016-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-105837767-A |
| titleOfInvention |
Cationic polymer gene vector and its preparation method and use |
| abstract |
The invention discloses a cationic polymer gene vector. N-(3-aminopropyl)methacrylamide and N-(1, 3-dihydroxy-2-propyl)methacrylamide as monomers undergo a polymerization reaction to produce an N-(1, 3-dihydroxy-2-propyl)methacrylamide-b-N-(3-aminopropyl)methacrylamide polymer through a reverse addition-fragmentation chain transfer polymerization method, and a guanidine group is coupled to the chain segment of N-(3-aminopropyl)methacrylamide to obtain an N-(1, 3-dihydroxy-2-propyl)methacrylamide-b-N-(3-guanidylpropyl)methacrylamide polymer. A ratio of the guanidinated N-(3-aminopropyl)methacrylamide chain segment to the polymer is in a range of 8.3-57%. The invention also provides a preparation method of the gene vector. The gene vector can carry a gene drug and has good biocompatibility and a large application prospect. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112807440-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106893054-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106893054-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021121068-A1 |
| priorityDate |
2016-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |