http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105837592-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-10 |
| filingDate | 2015-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105837592-B |
| titleOfInvention | Phloroglucin a pair of horses going side by side abietane diterpene-kind compound and preparation method thereof and medicinal usage |
| abstract | The invention belongs to pharmaceutical technology fields, are related to phloroglucin a pair of horses going side by side abietane diterpene-kind compound and preparation method thereof and medicinal usage, are especially preparing the purposes of protein-tyrosine phosphatase 1B inhibitor.The present invention is from Chloranthaceae (Chloranthaceae) Chloranthus plant southeast tree (Chloranthus oldhami, also known as C. oldhami, four leaves gold) herb or root extracting and developing obtain, have PTP 1B (PTP1B) inhibitory activity new phloroglucin a pair of horses going side by side abietane diterpene-kind compound (structure such as following formula), wherein R 1 、R 2 For methyl or methylol；R 3 For long-chain olefin.It is tested through Bioactivity, the results showed that, the compound has significant PTP1B inhibitory activity, available for the disease medicament for preparing prevention, delay or treat diabetes, obesity and its complication and other PTP1B are mediated. 。 |
| priorityDate | 2015-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 163.