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filingDate 2016-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105833294-B
titleOfInvention A kind of integrated peptide dendrimer assembly of biological response type diagnosis and treatment and its preparation method and application
abstract The present invention provides a kind of integrated peptide dendrimer assemblies of biological response type diagnosis and treatment, which is characterized in that including peptide dendrimer system and anti-tumor drug presoma;The peptide dendrimer system includes peptide dendrimer and imaging molecule, peptide dendrimer includes reversible chemical key and carboxyl, imaging molecule includes reversible chemical key or the functional group that can react with reversible chemical key, imaging molecule causes peptide dendrimer crosslinking, forms peptide dendrimer system;The anti-tumor drug presoma is made by anti-tumor drug by physical or chemical treatment, and anti-tumor drug presoma and peptide dendrimer system pass through weak interaction formation self assembly unit.Peptide dendrimer self-assembly of the invention has the advantages that stable structure, the biological signals in response to internal feature, collection Clinics and Practices one.
priorityDate 2016-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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