http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105820198-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y201-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-56 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-56 |
| filingDate | 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105820198-B |
| titleOfInvention | Puromycin derivative as well as preparation and application thereof |
| abstract | The invention discloses a puromycin derivative as shown in the formula (I) as well as preparation and application thereof. A novel compound 12-demethylation-dutomycin which can inhibit gram positive bacteria is produced by using an engineering biological synthesis method for a first time, the bacteriostatic activity of b12-demethylation-dutomycin on gram positive bacteria is remarkably higher than that of a natural compound dutomycin as source of b12-demethylation-dutomycin, the yield of a method for producing the compound 12-demethylation-dutomycin for inhibiting gram positive bacteria by using the engineering biological synthesis method and an extraction process of the method can be 44mg/L at most, raw material sources are not limited, the operation process is easy to control, and the production cost is low. |
| priorityDate | 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.