http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105806985-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
filingDate | 2016-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105806985-B |
titleOfInvention | A kind of assay method of vomiting nut aglycon biological sample |
abstract | The present invention relates to a kind of assay method of vomiting nut aglycon biological sample, belong to pharmaceutical technology field.The method detects concentration of the vomiting nut aglycon in biological sample using ultra-performance liquid chromatography electrospray ionization tandem mass spectrography, and wherein biological sample uses methyl alcohol as precipitation solvent;Mobile phase is made up of 0.1% formic acid water and methyl alcohol in liquid-phase condition, gradient elution;Cycloastragenol as vomiting nut aglycon Determination of Biological Samples internal standard.The vomiting nut aglycon biological sample LC MS MS determination methods set up of the present invention have reached Chinese Pharmacopoeia versions in 2015 and SFDA2014 promulgations at aspects such as the degree of accuracy, precision, specificity, stability, extraction recovery and matrix effects《Chemicals Non-clinical Pharmacokinetics investigative technique guideline》Analysis requirement to biological sample. |
priorityDate | 2016-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.